Pregnancy may be undergone without unusual risk in the absence of residual cardiac defects or stenosis of the aorta, either at the site of the aortic arch repair or in the left ventricular outflow tract. Because of the risk of complications due to the increased cardiac output, the expectant patient should be monitored regularly by her cardiologist.

Anyone with congenital heart disease, repaired or non-repaired, should consult with their cardiologist prior to becoming pregnant to review the risks.

Because interrupted aortic arch results commonly from a genetic defect, families should have genetic counseling before considering pregnancy.